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1.
Artigo em Inglês | MEDLINE | ID: mdl-34300056

RESUMO

Older age and comorbidities in hemodialysis patients determines the use of tunneled catheters as vascular access despite their reported clinical and mortality disadvantages. This prospective matched study analyzes the impact of permanent catheters on inflammation and mortality in hemodialysis patients; We studied 108 patients, 54 with AV-fistula (AVF) and 54 with indwelling hemodialysis catheters (HDC) matched by sex, age, diabetes and time under renal-replacement therapy comparing dialysis efficacy, inflammation and micro-inflammation parameters as well as mortality. Cox-regression analysis was applied to determine predictors of mortality, HDC patients presented higher C-reactive-protein (CRP) blood levels and percentage of pro-inflammatory lymphocytes CD14+/CD16+ with worse dialysis-efficacy parameters. Thirty-six-months mortality appeared higher in the HDC group although statistical significance was not reached. Age with a Hazard Ratio (HR) = 1.06, hypoalbuminemia (HR = 0.43), hypophosphatemia (HR = 0.75) and the increase in CD14+/CD16+ monocyte count (HR = 1.02) were predictors of mortality; elder patients dialyzing through HDC show increased inflammation parameters as compared with nAVF bearing patients, although they do not present a significant increase in mortality when matched by covariates. Increasing age and percentage of pro-inflammatory monocytes as well as decreased phosphate and serum-albumin were predictors of mortality and indicate the main conclusions or interpretations.


Assuntos
Derivação Arteriovenosa Cirúrgica , Cateteres Venosos Centrais , Idoso , Humanos , Inflamação , Estudos Prospectivos , Diálise Renal/efeitos adversos
2.
Enferm. nefrol ; 22(3): 274-283, jul.-sept. 2019. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-187884

RESUMO

Objetivo: El objetivo del presente estudio fue analizar la Calidad de Vida Relacionada con la Salud en pacientes hemodiálisis y su relación con la ansiedad y la depresión. Pacientes y Método: Se estudiaron 122 pacientes en hemodiálisis, con una edad de 66,47+/-14,2 años (34,4% mujeres). Se realizó un estudio descriptivo y transversal, en el área de influencia del Servicio de Nefrología del Hospital Reina Sofía de Córdoba. Se estudió la Calidad de Vida Relacionada con la Salud (cuestionario KDQOL-SF), Ansiedad y Depresión (cuestionario Escala de Ansiedad y Depresión de Goldberg) y la comorbilidad asociada. Resultados: En el KDQOL, las dimensiones más afectadas fueron: Situación Laboral, Carga de la Enfermedad Renal, Función Sexual y Sueño. En las dimensiones del cuestionario SF, las áreas más afectadas fueron: Rol Físico, Salud General y Función Física. El 42,6% de los pacientes presentaron probabilidad de tener ansiedad, el 52,5% depresión, y el 32,8% presentaban la probabilidad de padecer ambas alteraciones (ansiedad y depresión). La ansiedad y la depresión se asociaron de forma significativa a peores puntuaciones en todas las dimensiones del cuestionario KDQOL-SF. Conclusiones: Los pacientes en hemodiálisis presentan peor calidad de vida que la población sana de referencia, especialmente en las dimensiones Carga de la enfermedad renal, Sueño, Salud general, Vitalidad, Función física y Rol físico. Esta disminución de la calidad de vida está relacionada con la probabilidad de padecer ansiedad y/o depresión. El sexo femenino, la comorbilidad asociada y el tiempo en hemodiálisis, se asocian también a peor calidad de vida


Objective: The aim of the present study was to analyze the health-related quality of life in hemodialysis patients and their relationship with anxiety and depression. Material and Method: One hundred and twenty-two hemodialysis patients were studied, with an age of 66.47 +/- 14.2 years (34.4% women). A descriptive and cross-sectional study was carried out in around the Nephrology Unit of the Reina Sofía University Hospital of Cordoba. The health-related quality of life (KDQOL-SF questionnaire), anxiety and depression (Goldberg Anxiety and Depression Scale questionnaire) and associated comorbidity were studied. Results: In the KDQOL scale, the most affected dimensions were: Work Status, Kidney Disease Burden, Sexual Function and Sleep. In the dimensions of the SF questionnaire, the most affected areas were: Physical Role, General Health and Physical Function. 42.6% of the patients presented probability of having anxiety, 52.5% depression, and 32.8% had the probability of suffering both alterations (anxiety and depression). Anxiety and depression were significantly associated with worse scores in all dimensions of the KDQOL-SF questionnaire. Conclusions: Hemodialysis patients have a worse quality of life than the healthy reference population, especially in the Kidney Disease Burden, Sleep, General health, Vitality, Physical Function and Physical Role dimensions. This decrease in the quality of life is related to the probability of suffering anxiety and/or depression. Female sex, associated comorbidity and length of time on hemodialysis are also associated with a worse quality of life


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Diálise Renal/psicologia , Insuficiência Renal Crônica/psicologia , Qualidade de Vida/psicologia , Ansiedade/psicologia , Depressão/psicologia , Dor/psicologia , Diálise Renal/enfermagem , Insuficiência Renal Crônica/terapia , Perfil de Impacto da Doença , Questionário de Saúde do Paciente/estatística & dados numéricos
3.
Enferm. nefrol ; 21(3): 255-262, jul.-sept. 2018. tab
Artigo em Espanhol | IBECS | ID: ibc-174062

RESUMO

Objetivos: El objetivo del presente estudio fue analizar la relación existente entre el optimismo disposicional y el apoyo social, con los síntomas somáticos en un grupo de pacientes en hemodiálisis. Pacientes y Método: Se estudiaron 80 pacientes en hemodiálisis, con una edad de 65,20±16,47 años (36,3% mujeres). Se realizó un estudio descriptivo y transversal, en el Servicio de Nefrología de Hospital Reina Sofía de Córdoba. Se estudió el Optimismo Disposicional (cuestionario LOT-R), el Apoyo Social (cuestionario Duke-UNC), los síntomas (Escala de Síntomas Somáticos Revisada) y la comorbilidad asociada. Resultados: La media del LOT-R fue 21,19±5,04 puntos y la mediana 21 (8-30). Se utilizó la mediana del LOT-R para dividir a los pacientes en Pesimistas Disposicionales (<21) y Optimistas Disposicionales (≥21). Aunque edad y comorbilidad fueron más altas en el grupo Optimista, las diferencias no fueron significativas. Los Optimistas presentaron menos síntomas que los Pesimistas, aunque sin diferencias significativas. Los pacientes con Apoyo Social más bajo presentaron más síntomas, aunque sin diferencias significativas. Tampoco se encontraron diferencias significativas en el Apoyo Social recibido entre Optimistas frente a los Pesimistas. Las mujeres presentaron más síntomas gastrointestinales y músculoesqueléticos. La edad se correlacionó estadísticamente con la comorbilidad. Conclusiones: Al menos en nuestra muestra, en los pacientes en hemodiálisis, ni el Optimismo Disposicional ni el Apoyo Social parecen influir en la aparición de síntomas somáticos, ni tampoco el Apoyo Social tiene influencia en el Optimismo Disposicional. Las mujeres presentan más síntomas gastrointestinales y músculoesqueléticos que los hombres. A más edad más comorbilidad asociada


Objectives: The aim of the present study was to analyze the relationship between dispositional optimism and social support with somatic symptoms in a group of patients on hemodialysis. Patients and Method: We studied 80 patients on hemodialysis, with an average age of 65.20 ± 16.47 years (36.3% women and 63.7% men). A descriptive and cross-sectional study was carried out in the Nephrology Service of the Reina Sofía Hospital in Córdoba. The LOT-R questionnaire for Dispositional Optimism and the Revised Somatic Symptoms Scale were used. Social Support and associated comorbidity were also analyzed. Results: The mean LOT-R was 21.19±5.04 and the median 21 (8-30). The median LOT-R was used to divide patients between pessimists (<21) and optimists (≥21). Although age and comorbidity were higher in the optimistic group, not being significant differences. Although optimists presented fewer symptoms than pessimists, there were no significant differences. Similarly, although patients with lower Social Support presented more symptoms, also without significant differences. When the Social Support of the optimists was compared with the pessimists, no differences were found. Statistical relationship of age was found with comorbidity and cardiovascular symptoms. Conclusions: At least in our sample, in hemodialysis patients, neither Dispositional Optimism nor Social Support seem to influence the appearance of somatic symptoms, nor does Social Support influences Dispositional Optimism. Women have more gastrointestinal and musculoskeletal symptoms than men. The older, the more associated comorbidity


Assuntos
Humanos , Insuficiência Renal Crônica/terapia , Diálise Renal/psicologia , Cuidados de Enfermagem/métodos , Otimismo/psicologia , Enquadramento Psicológico , Estudos Transversais , Apoio Social , Sintomas Inexplicáveis , Transtornos Somatoformes/psicologia , Comorbidade , Distribuição por Idade e Sexo
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